Chemical Control

Chemical indicators; simply, the specific sterilisation to which the package has been exposed at the point of insertion
conditions. However, chemical indicators can be used in a certain temperature-time range.
They are manufactured to work and never work correctly outside these ranges.

For example, if the temperature is above the recommended range, the indicator will not work correctly due to localised overheating in the package.
will change colour earlier than expected. However, without sufficient humidity, high
microbial death will be much slower at temperature. Chemical indicators will provide
The value of the information depends on the class, number and location of the indicator in the steriliser. This is the
indicators identified during process validation and representative of the entire steriliser
in areas that are likely to be able to analyse the colour of a chemical indicator.

If a chemical indicator does not have the required colour change after cycling, it should never be
should not be interpreted as the indicator is not working, it must be used during the sterilisation process.
should be evaluated as an error and the process should be repeated in terms of the following possible problems
should be reviewed:
- Does the steriliser have a malfunction that prevents it from reaching the specified values?

- Is there a change in the packaging material?

- Is there a change in the amount of material in the package?

- Has routine maintenance and calibration of the steriliser been carried out properly and on time?

- Has the correct sterilisation programme been used?

- Was the chemical indicator used according to the manufacturer's recommendation?

- Is there an external problem that may affect the steriliser cycle (steam pressure, current
speed and the uncondensed gases it contains).


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Sterilizasyon Dezenfeksiyon Rehberi 2015